How does muse work

With every session you earn points, and can adjust your goal to fit your needs. Muse connects to your mobile device via Bluetooth. United Kingdom. United States. Rest of Latin America. United Arab Emirates. Rest of Middle East. New Zealand. Rest of Asia and Oceana. Rest of Europe. Most Popular. North America. Latin America and Caribbean. Middle East.

Asia and Oceania. Enter your info for a chance to win a free Muse 2. No, thank you. Muse 2. Muse will guide you to a calm mind. Patients should be individually titrated to the lowest dose that is sufficient for sexual intercourse.

The lower doses of MUSE mcg or mcg are recommended for initial dosing. If necessary, the dose should be increased or decreased on separate occasions in a stepwise manner until the patient achieves an erection that is sufficient for sexual intercourse. MUSE should be used as needed to achieve an erection. The maximum frequency of use is 2 administrations per hour period.

Each MUSE is for single use only and should be properly discarded after use. MUSE is supplied in individual foil pouches containing one 1 system per pouch. MUSE is available in unit cartons containing six 6 systems. MUSE is available in the following 4 dosage strengths:. This pamphlet is a quick reference source on important information about MUSE for you and your partner. Before administering MUSE, please review the patient video and education booklet. These materials provide visual instruction and more detailed information as well as practical tips on how to use MUSE.

MUSE represents a unique approach for the treatment of erectile dysfunction, commonly called impotence. It is based on the discovery that the urethra the normal pathway for urine can absorb certain medications into the surrounding erectile tissues thereby creating an erection. There are 4 dose strengths available: , , , and micrograms. Your dose of MUSE will be determined by you and your physician. After administration, the erection process will begin within 5 — 10 minutes, and may last 30 — 60 minutes.

Erectile dysfunction is the inability to attain or maintain an erection sufficient for sexual intercourse. If you have a history of fainting be sure to discuss this with your doctor prior to using MUSE. If you do experience dizziness or feel faint, this may be due to the lowering of your blood pressure. Lie down immediately and raise your legs. If symptoms persist, call your doctor promptly. Because of the potential for these side effects, MUSE titration should be carried out under medical supervision.

Call your doctor for medical advice about side effects. To report side effects, contact Meda Pharmaceuticals Inc. It is assumed that you and your doctor have determined the proper dose of MUSE. If you suspect that your dose needs to be increased or decreased to achieve the response that works best for you, please call your doctor to determine if your dose needs to be reevaluated.

Do not use MUSE more than twice in a hour period. The most common reported side effects observed in women whose partners use MUSE are mild vaginal itching or burning. Using a water-based lubricant can help to make vaginal penetration easier.

Your partner may want to consult her health care provider if she has not had sexual intercourse for an extended period of time. Because MUSE has not been tested during human pregnancy, it is recommended that couples use adequate contraception if the female partner is of childbearing potential. MUSE will not protect you or your partner from sexually transmitted diseases like chlamydia, gonorrhea, herpes simplex virus, viral hepatitis, human immunodeficiency virus HIV - the virus that causes AIDS , human papilloma virus genital warts , and syphilis.

Latex condoms can protect against these sexually transmitted diseases. It is recommended that MUSE be stored in a refrigerator. MUSE should not be exposed to high temperatures or placed in direct sunlight. When traveling, store MUSE in a portable ice pack or cooler. Do not store in the trunk of a car or in baggage storage areas where MUSE may be exposed to extremes in temperature. After you have administered MUSE, it is important to sit, or preferably stand or walk about for 10 minutes while the erection is developing.

This increases blood flow to the penis and will enhance your erection. At first, you may feel some minor discomfort from insertion. Urinating prior to administration will reduce the chance of discomfort or abrasions and is important for dissolving the medicated pellet. Be sure to straighten your penis to its full length when inserting the MUSE applicator.

With repeated use, administration will become much easier. Most of the side effects reported in men are relatively minor and include burning and aching in the penis and groin. Rarely noted are prolonged erection, light-headedness, dizziness, fainting, rapid pulse, and swelling of the leg veins.

If you feel dizzy, light-headed, faint, or experience rapid pulse, lie down immediately and raise your legs. You can begin sexual activity, but having the man lie down, especially on his back shortly after administration, is not recommended. This will reduce blood flow to the penis and may reduce the erection. It is important to sit, stand or walk about for 10 minutes after administration.

Many couples have used this time to incorporate various types of foreplay. After this initial period, you can assume different positions leading to sexual intercourse. Some couples have noticed that the erection is better maintained in positions that favor blood flow into the penis during intercourse.

Please review the video and patient starter booklet available from your doctor which illustrates various positions that will enhance your erection. An erection should begin within 5 — 10 minutes after administering MUSE. The duration of effect is approximately 30 — 60 minutes. What will the erection be like? How will it compare to the erections I had when I was younger? An effective dose of MUSE should produce an erection sufficient for sexual intercourse. MUSE may not create an erection such as those you experienced when you were younger.

Some patients may experience some mild pain and aching in the penis or groin area. Also, your erection may continue after orgasm. You and your physician will determine the appropriate dose of MUSE. If your erection cannot be maintained for the time needed to have foreplay and sexual intercourse, you may need to have your dose increased.

Similarly, an erection that lasts longer than desired may require a dose decrease. Call your doctor if you suspect you may require a dosing adjustment. Your penis may feel full, warm, and somewhat sensitive to the touch. These effects are normal and may last a few hours. After you have administered MUSE, replace the cover on the applicator, place in the opened foil pouch, fold, and discard as normal household waste. An application of ice packs to the inner thigh may shorten the duration of the erection, since the cold will restrict blood flow to the penis.

If used, ice packs should be applied alternately to each inner thigh for a period not exceeding 10 minutes. Please read patient instruction leaflet regarding usage and storage. Absorption MUSE is designed to deliver alprostadil directly to the urethral lining for transfer via the corpus spongiosum to the corpora cavernosa.

Distribution Following MUSE administration, alprostadil is absorbed from the urethral mucosa into the corpus spongiosum. Metabolism Alprostadil is rapidly metabolized locally by enzymatic oxidation of the hydroxyl group to keto-PGE 1. Excretion After intravenous administration of tritium-labeled alprostadil in man, labeled drug disappears rapidly from the blood in the first 10 minutes, and by 1 hour radioactivity in the blood reaches a low level.

Geriatrics The effects of age on the pharmacokinetics of alprostadil have not been evaluated. Known hypersensitivity to alprostadil. Sickle cell anemia or trait, thrombocythemia, polycythemia, multiple myeloma: MUSE is contraindicated in patients who are prone to venous thrombosis or who have a hyperviscosity syndrome and are therefore at increased risk of priapism rigid erection lasting 6 or more hours.

A complete medical history and physical examination should be undertaken to exclude reversible causes of erectile dysfunction prior to the initiation of MUSE therapy. Cardiovascular effects: During in-clinic dosing, patients should be monitored for symptoms of hypotension, and the lowest effective dose of MUSE should be prescribed. Hematologic effects: Patients administering MUSE improperly may be at risk of urethral abrasion resulting in minor bleeding or spotting. Patients on anticoagulant therapy or with bleeding disorders may be at higher risk of bleeding.

Resumption of sexual activity: Sexual intercourse is considered a vigorous physical activity, and it increases heart rate as well as cardiac work. Physicians may want to examine the cardiac fitness of patients prior to treating erectile dysfunction. Nevertheless, these events are a potential risk of pharmacologic therapy and can cause penile injury.

Physicians should lower the dose or consider discontinuing MUSE treatment in any patient who develops priapism or prolonged erection. Although formal studies have not been conducted, the concomitant use of MUSE and anti-hypertensive medications may increase the risk of hypotension.

It is therefore advised that caution be used in the administration of MUSE to individuals on anti-hypertensive medications. In addition, the presence of medications in the circulation that attenuate erectile function may influence the response to MUSE. Sexual Preference: There is no experience in homosexual men and no experience with other than vaginal intercourse.

Information for Patients Patients should be informed that MUSE offers no protection from the transmission of sexually transmitted diseases. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term carcinogenicity studies of alprostadil have not been conducted.